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Can HBOT Help in Treating Long COVID Symptoms
Hyperbaric Oxygen Therapy (HBOT) has long been recognized for its benefits in wound healing, decompression sickness, and carbon monoxide poisoning. But in the wake of the COVID-19 pandemic, many researchers and clinicians are now asking: Can HBOT help in treating long COVID symptoms?
This article dives into the science behind HBOT, its proposed role in addressing long COVID, and current case studies exploring its efficacy. As long COVID continues to affect millions worldwide, novel treatment avenues like oxygen therapy are gaining attention for their potential to ease symptoms and support recovery.

What Is HBOT and How Does It Work?
Hyperbaric Oxygen Therapy (HBOT) involves breathing 100% pure oxygen in a pressurized environment—typically inside a hyperbaric chamber. This increases the amount of oxygen your blood can carry, which helps promote healing and reduce inflammation.
HBOT is used to treat a wide range of conditions, including:
- Chronic wounds
- Radiation injuries
- Sudden hearing loss
- Severe anemia
- Brain injuries
According to Johns Hopkins Medicine, the increased oxygen enhances the body’s natural healing processes, particularly in areas where blood flow is limited.
Understanding Long COVID: Symptoms and Challenges
Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), refers to lingering symptoms that persist weeks or months after initial recovery from COVID-19. These symptoms vary widely and may include:
- Fatigue
- Brain fog
- Shortness of breath
- Chest pain
- Joint or muscle aches
- Autonomic dysfunction
According to the Centers for Disease Control and Prevention (CDC), over 1 in 5 adults under age 65 may experience some form of long COVID after surviving the virus.
How HBOT May Address Long COVID Symptoms
HBOT is believed to alleviate long COVID symptoms by improving cellular oxygenation, decreasing neuroinflammation, and enhancing mitochondrial function—mechanisms often impaired in long COVID patients.
1. Reducing Inflammation
One of the hallmark challenges of long COVID is persistent, low-grade inflammation. HBOT has been shown to modulate inflammatory cytokines and reduce oxidative stress, as outlined in a study published in Frontiers in Neurology.
2. Restoring Cognitive Function
Cognitive issues such as "brain fog" and memory problems are commonly reported. Preliminary clinical trials, including one by Israel's Tel Aviv University, have demonstrated that HBOT significantly improved cognitive performance in long COVID patients, possibly due to its ability to stimulate neurogenesis and improve cerebral blood flow.
For more on cognitive recovery, explore this hyperbaric study summary from News-Medical.net.
3. Improving Energy and Fatigue Levels
Low energy and chronic fatigue are among the most debilitating symptoms. HBOT helps repair mitochondrial damage and increase ATP production—key for restoring normal energy levels.
Clinical Evidence Supporting HBOT for Long COVID
A. Randomized Controlled Trials
The first randomized controlled trial on HBOT for long COVID was conducted in Israel. It found that participants receiving HBOT showed significant improvements in fatigue, attention, and executive function compared to those in the control group.
B. Case Studies and Anecdotal Evidence
Numerous anecdotal cases have also reported dramatic recoveries, particularly among patients with severe fatigue and respiratory issues. These findings have encouraged more clinics worldwide to begin offering oxygen therapy for long COVID patients on a case-by-case basis.
Safety and Risks of HBOT for Long COVID
While HBOT is generally safe when administered by trained professionals, it’s essential to understand potential side effects:
- Barotrauma (ear or sinus pressure)
- Temporary vision changes
- Oxygen toxicity (rare)
- Claustrophobia in closed chambers
The FDA recommends that HBOT only be used under proper supervision and for medically approved conditions.
However, many experts argue that off-label use for long COVID may be warranted due to the severity and longevity of symptoms in some individuals.
Who Should Consider HBOT?
HBOT may be beneficial for long COVID patients who:
- Experience persistent fatigue or brain fog
- Have undergone other treatments without improvement
- Are medically stable but suffering ongoing post-COVID issues
That said, patients should consult with their healthcare providers to determine eligibility. A customized treatment plan should consider symptom severity, overall health, and response to other therapies.
Cost and Accessibility of HBOT
The cost of HBOT sessions can vary widely:
- Clinical centers: $200–$400 per session
- Home units: $5,000–$20,000 for a portable chamber
Some providers and health insurers may cover sessions for long COVID, particularly if recommended by a physician.
For comparisons, see this breakdown on HBOT chamber pricing from Hyperbaric Central.
Future of HBOT in Long COVID Treatment
As more long COVID clinics emerge globally, HBOT may become a staple in multimodal recovery strategies. Ongoing studies across the U.S., UK, and Israel continue to investigate:
- Optimal treatment duration and pressure levels
- Biomarkers for HBOT responsiveness
- Long-term cognitive and physical outcomes
Conclusion: Is HBOT a Viable Solution for Long COVID?
In the evolving landscape of long COVID treatments, hyperbaric oxygen therapy presents a promising, science-backed option—especially for patients grappling with persistent cognitive and fatigue symptoms. While not yet FDA-approved specifically for long COVID, early data and patient reports suggest substantial benefits.
As research expands, HBOT could play a significant role in restoring quality of life for millions of long COVID sufferers.
by Summer William on 2025-07-25 11:36:16
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